THE LEVEL OF OXIDATIVE STRESS METABOLITES IN AN EXPERIMENTAL MODEL WITH PERIODONTITIS
-
Published:2022-03-24
Issue:3
Volume:12
Page:
-
ISSN:2199-885X
-
Container-title:Archiv Euromedica
-
language:
-
Short-container-title:ArveMED
Author:
Tarasova TatyanaORCID,
Balykova Larisa,
Khaydar DalilaORCID,
Gurova OlgaORCID,
Zakhvatov Alexey,
Korovyakova Elina,
Korovyakova ElinaORCID,
Mosina Larisa,
Tarasov Roman,
Alekseeva Maria Francisca
Abstract
In people worldwide, chronic periodontitis occurs in 10-15% of cases. Prolonged inflammation of periodontal tissues contributes to the formation of oxidative stress. The purpose of this study was to evaluate the level of malondialdehyde and superoxide dismutase (as indicators of oxidative stress) in periodontitis in rats. For this, in the main group of rats (n=10) a model of ligature periodontitis was created. The control group of rats (n=10) was intact. As a result, in periodontitis, the level of malondialdehyde doubled. We also found an inverse relationship between the level of lipid damage and superoxide dismutase activity. Conclusions. The level of metabolites of redox processes is significantly increased in periodontitis. This confirms a significant increase in the indicators of malondialdehyde. A decrease in superoxide dismutase activity leads to a low antioxidant status in rats.
Publisher
European Scientific Society
Subject
General Medicine,General Chemistry