ASSESSMENT OF REGULATORY AND REPARATIVE OSTEOGENESISIN AUGMENTATION AREA BASED ON ORAL FLUID METABOLIC PARAME

Abstract

Cases of serious atrophy of the alveolar processes occurring during dental implantation could be restored saving the respective bone volume. There is also a need for postoperative monitoring of the physiological osteogenesis effectiveness in the peri-implant zone. Our paper offers an assessment of regulatory and reparative osteogenesis in the augmentation zone subject to the oral fluid (OF) metabolic parameters obtained from 59 patients. Biochemical methods for oral fluid examination are noninvasive approaches that allow identifying pathologies at the tissue and cellular level. The proposed metabolic indices of collagen C-telopeptide, osteocalcin, alkaline phosphatase (AP) and parathyroid hormone helped identify augmentation zone of disturbed reparation in 6.8% of patients, whereas the worst complications were to be observed one month after the implantation. Through this period, however, orthopantogram featured no pathological change. Given that, the biochemical markers of bone tissue remodeling are employed for early identification and developing a forecast regarding treatment effectiveness.