Abstract
The aim of the work was to study the effect of isotretinoin preparations with different bioavailability (acnecutane and roaccutane) on blood and saliva crystallization in patients with severe forms of acne. The studies were conducted in two main groups: 25 patients used the drug Acnecutan in the treatment, 10 patients used the usual isotretinoin (Roaccutane). A study of the nature of own and initiated crystallization of blood serum and saliva was carried out by our techniques. The results of the study allow us to conclude that the tesicrystalloscopic "pattern" of the biological environment of patients with acne differs significantly from that characteristic of practically healthy people. Based on biocrystalloscopic testing, it was found that in the course of treatment with isotretinoin drugs, a partial normalization of indicators was observed, which occurs mainly when using Acnecutan.
Publisher
European Scientific Society