THE EFFECT OF ASSOCIATED CHRONIC OBSTRUCTIVE PULMONARY DISEASE ON THEINDICATORS OF PRECURSOR OFTYPE B NATURAURETIC PEPTIDE AND PROADRENOMEDULLIN AMONG PATIENTSWITH ISCHEMIC CA

Author:

Myasoedova E.I.,Voronina L.P,Popov E.A.,Sevostyanova I.V.,Mukhambetova G.N.,Polunina O.S.,Perova N.Y.,Prokofieva T.V.

Abstract

The study showed that a statistically significant increase of NT-proBNP levels (779,36 [473; 2193] pg/ml) and MR-proADM (1,72 [1,56; 1,98] nmol/l) relative to the control values (69.90 [48.96; 91.00] pg / ml and 0,49 [0,18; 0,58] nmol/l, respectively) is common for the patients with ischemic cardiomyopathy. The presence of concomitant chronic obstructive pulmonary disease among the patients is associated with more pronounced increase in the level of NT-proBNP (872,37 [510; 2355] pg/ml) and MR-proADM (1,97 [1,75; 2,19] nmol/l) compared with a group of patients with isolated ischemic cardiomyopathy. This can be considered as one of the compensation links for this comorbid combination

Publisher

European Scientific Society

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