Rational sequence of monoclonal antibodies in the treatment of non-resectable head and neck squamous cell carcinoma-Reference-Cited by-同舟云学术

Rational sequence of monoclonal antibodies in the treatment of non-resectable head and neck squamous cell carcinoma

Published:2022-04-11 Issue:1 Volume:12 Page:35-52
ISSN:2411-4634
Container-title:Head and Neck Tumors (HNT)
language:
Short-container-title:Opuholi golovy i šei

Author:

Bolotina L. V.¹^ORCID,Ustinova T. V.¹^ORCID,Dеshkina T. I.¹^ORCID,Golubev P. V.¹^ORCID,Lyubavina N. N.¹,Fedenko A. A.¹,Kaprin A. D.²^ORCID

Affiliation:

1. P.A. Herzen Moscow Oncology Research Institute – a branch of the National Medical Radiology Research Center, Ministry of Health of Russia

2. P.A. Herzen Moscow Oncology Research Institute – a branch of the National Medical Radiology Research Center, Ministry of Health of Russia; Рeoples’ Friendship University of Russia

Abstract

This article discusses current approaches to first-line chemotherapy for non-resectable head and neck squamous cell carcinoma and describes factors affecting the choice of treatment regimen according to the results of randomized clinical trials. We provide a rationale for creating a long-term strategy of chemotherapy in different clinical situations. We also report two cases of concomitant administration of cetuximab and platinum-based therapy as an example of high efficacy of monoclonal antibodies.

Publisher

Publishing House ABV Press

Subject

Pharmacology (medical),Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology,Otorhinolaryngology,Surgery

Reference26 articles.

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