Changing the phenotype of breast cancer in the process treatment: literature review

Abstract

A review of the literature concerning the issue of changing the phenotype of breast cancer during treatment is presented. In the Russian Federation, breast cancer (breast cancer) occupies a leading position in the structure of morbidity and mortality of female oncological diseases. Many retrospective studies have reported changes in the expression of bio-markers in surgical samples after neoadjuvant therapy. The study of changes in biological subtypes can change approaches to therapy and contribute to an increase in survival rates in such patients. Based on these data, we can talk about the need for repeated assessments of the tumor biotype during treatment, which contributes to an optimal and personalized approach to breast cancer therapy.