Cytological criteria of differentiation of phyllodes tumor of the breast and fibroadenoma

Author:

Grigoruk О. G.1

Affiliation:

1. Altai Regional Oncology Dispensary; Altai State Medical University, Ministry of Health of Russia

Abstract

The article is devoted to the determination of the cytological criteria of differentiation of fibroadenoma and phyllodes tumor. By means of multivariate analysis the 11 most informative cellular signs of fibroadenoma, juvenile fibroadenoma and benign phyllodes tumors were identified. According to the discriminant analysis, only 37.97 % of patients with benign phyllodes tumors are classified correctly, that indicates the difficulties of differentiation of these tumors. Some cellular signs of fibroadenoma, borderline and malignant phyllodes tumor allow to diagnose these forms of tumors.

Publisher

Publishing House ABV Press

Subject

Pharmacology (medical),Obstetrics and Gynaecology,Radiology Nuclear Medicine and imaging,Oncology,Surgery

Reference11 articles.

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3. Jacklin R.K., Ridgway P.F., Ziprin P. et al. Optimising preoperative diagnosis in phyllodes tumour of the breast. J Clin Pathol 2006;59:454–9. DOI: 10.1136/jcp.2005.025866.

4. Abe M., Miyata S., Nishimura S. et al. Malignant transformation of breast fibroadenoma to malignant phyllodes tumor: long-term outcome of 36 malignant phyllodes tumors. Breast Cancer 2011;18:268–72. DOI: 10.1007/s12282-009-0185-kh.

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