Individual approach to choosing an appropriate regimen of adjuvant hormone therapy in patients with early-stage breast cancer

Author:

Slonimskaya E. M.1ORCID,Doroshenko A. V.1ORCID,Kazantseva P. V.1ORCID,Tarabanovskaya N. A.1ORCID,Vernadsky R. Yu.1

Affiliation:

1. Oncology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences

Abstract

Adjuvant hormone therapy is considered the gold standard of therapy for hormone receptor-positive operable breast cancer. The approach to adjuvant hormone therapy in premenopausal patients has changed significantly in recent years. This change was caused by clinical trials, which have confirmed the advantage of adding ovarian suppression to tamoxifen or aromatase inhibitors monotherapy. Individual approach to choosing an appropriate regimen of adjuvant hormone therapy in premenopausal patients with breast cancer should be based on the assessment of risks for relapse, expected effectiveness of treatment and evaluation of drug safety.

Publisher

Publishing House ABV Press

Subject

Pharmacology (medical),Obstetrics and Gynaecology,Radiology Nuclear Medicine and imaging,Oncology,Surgery

Reference25 articles.

1. Zlokachestvennye novoobrazovaniya v Rossii v 2015 godu (zabolevaemost' i smertnost'). Pod red. A.D. Kaprina, V.V. Starinskogo, G.V. Petrovoi M.: MNIOI im. P.A. Gertsena – filial FGBU «NMITs radiologii Minzdrava Rossii», 2017. [Malignant tumors in Russia in 2015 (incidence and mortality). Eds.: A. D. Kaprin, V. V. Starinskiy, G. V. Petrova. Moscow: P. Herzen Moscow Oncology Research Institute – a branch of the National Medical Research Radiology Center, Ministry of Health of Russia, 2017. (In Russ.)].

2. SEER Cancer Statistics Review, 1975–2014. N. Howlader, A.M. Noone, M. Krapcho, D. Miller , K. Bishop, C.L. Kosary, M. Yu, J. Ruhl, Z. Tatalovich, A. Mariotto, D.R. Lewis, H.S. Chen, E.J.Feuer, K.A. Cronin (eds). Bethesda, MD: National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/csr/1975_2014/, based on November 2016 SEER data submission, posted to the SEER web site, April 2017.

3. Lambertini M., Pinto A.C., Ameye L. et al. The prognostic performance of adjuvant! Online and Nottingham prognostic index in young breast cancer patients. Br J Cancer 2016;115:1471–8.

4. Partridge A.H., Hughes M.E., Warner E.T. et al. Subtype-dependent relationship between young age at diagnosis and breast cancer survival. J Clin Oncol 2016;34:3308–14.

5. Senkus E., Kyriakides S., Penault-Llorca F. et al. Primary breast cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 2013;24(Suppl 6):vi7–vi23.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3