Author:
Ataullakhanov F. I.,Rumyantsev A. G.
Abstract
In recent years, an active revision of ideas about the mechanisms of blood clotting has been performed. Traditional views were largely inaccurate, which is the main reason for the inconsistency of the modern standard set of coagulation tests. This set was found to be insensitive, especially to hypercoagulable disorders. In this paper, we consider modern concepts of how blood clotting occurs. From this consideration follows the need for a critical review of existing methods for assessing the status of hemostasis and a standard set of laboratory tests. The lecture ends with a brief examination of which methods are the most informative today and could form the basis of a new informative coagulation testing set.
Subject
Oncology,Hematology,Pediatrics, Perinatology, and Child Health
Reference24 articles.
1. Willoughby S., Holmes A., Loscalzo J. Platelets and cardiovascular disease. Eur J Cardiovasc Nurs 2002;1(4):273–88. doi: 10.1016/S1474-51510200038-5.
2. Panteleev M.A., Vasilyev S.A., Sinauridze E.I. et al. Practical coagulology. М.: Prakticheskaya meditsina, 2011. 192 p. (In Russ.).
3. Shmidt R., Tevs G. Human physiology. Vol. 2. М.: Mir, 2005. 314 p. (In Russ.).
4. Lim B.B., Lee E.H., Sotomayor M., Schulten K. Molecular basis of fibrin clot elasticity. Structure 2008;16(3):449–59. doi: 10.1016/j.str.2007.12.019.
5. Heemskerk J.W., Mattheij N.J., Cosemans J.M. Platelet-based coagulation: different populations, different functions. J Thromb Haemost 2013;11(1):2–16. doi: 10.1111/jth.12045.
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献