Epidemiological and clinical features of lymphoproliferative diseases in the head and neck region-Reference-Cited by-同舟云学术

Epidemiological and clinical features of lymphoproliferative diseases in the head and neck region

Published:2021-09-10 Issue:3 Volume:16 Page:105-117
ISSN:2413-4023
Container-title:Oncohematology
language:
Short-container-title:Onkogematologiâ

Author:

Kamolova F. Sh.¹^ORCID,Mudunov A. M.¹^ORCID,Zeynalova P. A.¹^ORCID,Grivtsova L. Yu.²^ORCID,Allakhverdieva G. F.³^ORCID,Azizyan R. I.¹^ORCID,Akhundov A. A.¹^ORCID,Zaderenko I. A.¹^ORCID,Bolotin M. V.¹^ORCID,Stelmakh D. K.¹^ORCID,Sokorutov V. I.¹,Il’kaev K. D.¹,Tsiklauri V. T.¹^ORCID,Gelfand I. M.¹^ORCID,Pak M. B.³^ORCID,Timofeeva O. L.³^ORCID,Ryabukhina Yu. E.³^ORCID,Abbasbeyli F. M.³^ORCID,Chzhao Ts.¹^ORCID

Affiliation:

1. N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

2. A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia

3. Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

Abstract

Background. Lymphomas are a heterogeneous group of the lymphoid and hematopoietic system tumors. Neoplastic process often develops in head and neck area, including the integumentary tissues, orbit, nasal cavity, paranasal sinuses, oral cavity, pharynx, salivary glands, thyroid gland, as well as neck lymph nodes. The difficulties of head and neck lymphomas diagnosis are significant, since very often there is a combined non-tumor pathology. The high heterogeneity of lymphomas in the head and neck area requires structuring knowledge about their epidemiology and clinical manifestations.Objective: to study the epidemiological and clinical features of the head and neck lymphoproliferative diseases, which will lead to an improvement in diagnostic quality of this nosology’s.Materials and methods. The frequency of head and neck lymphoproliferative diseases detection was estimated based on the study of epicrisis and clinical data of 174 patients hospitalized at the N.N. Blokhin National Medical Research Center of Oncology in the period from 2000 to 2020.Results. Taking into account the modern clinical and morphological classification of lymphomas of the World Health Organization (2017), information about the features of localization, characteristic signs of extranodal foci and lymph nodes is presented. Detection frequency of various subtypes non-Hodgkin’s and Hodgkin’s lymphomas were determined on a sufficient cohort of patients.Conclusion. Based on the analysis of clinical and morphological features of head and neck lymphomas, epidemiological and clinical features are described in detail, and differences in the symptoms and clinical manifestations of non-Hodgkin’s and Hodgkin’s lymphomas with a predominant head and neck involvement are revealed.

Publisher

Publishing House ABV Press

Subject

Oncology,Hematology

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