Pediatric follicular lymphoma: literature review and presentation of a rare clinical case-Reference-Cited by-同舟云学术

Pediatric follicular lymphoma: literature review and presentation of a rare clinical case

Published:2024-09-02 Issue:3 Volume:19 Page:122-131
ISSN:2413-4023
Container-title:Oncohematology
language:
Short-container-title:Onkogematologiâ

Author:

Volkova A. S.¹^ORCID,Valiev T. T.²^ORCID,Abramov D. S.³^ORCID,Tarakanova A. V.³^ORCID,Odzharova A. A.¹,Ryabukhina Yu. E.⁴^ORCID,Zeynalova P. A.⁵^ORCID

Affiliation:

1. N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

2. N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

3. Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia

4. Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

5. I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

Abstract

Follicular lymphoma is one of the most common non-Hodgkin’s lymphomas in adults. One of the rather rare variants of follicular lymphoma is pediatric follicular lymphoma. This variant, despite the name, is diagnosed not only in children, but also among young adults. Pediatric follicular lymphoma is characterized by early (I, II) stages, the absence or weak BCL2 expression, and the predominant absence of t(14;18)(q32;q21) translocation. Treatment tactics vary widely from radical surgical tumor resection with subsequent follow-up to chemoimmunotherapy with rituximab.This article presents a clinical case of advanced pediatric follicular lymphoma (stage III) in a 5-year-old patient. Using a combined treatment approach (surgery followed by immunochemotherapy) allowed to achieve a complete metabolic response which lasts more than a year.

Publisher

Publishing House ABV Press

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