Molecular genetic features of cutaneous T-cell lymphomas development on example of mycosis fungoides and Sezary syndrome-Reference-Cited by-同舟云学术

Molecular genetic features of cutaneous T-cell lymphomas development on example of mycosis fungoides and Sezary syndrome

Published:2022-01-29 Issue:1 Volume:17 Page:65-74
ISSN:2413-4023
Container-title:Oncohematology
language:
Short-container-title:Onkogematologiâ

Author:

Khadzhieva M. B.¹^ORCID,Zakharova E. S.²,Kalinina E. V.²,Abramov D. S.²^ORCID,Rumyantsev A. G.²,Larin S. S.²^ORCID

Affiliation:

1. Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology

2. Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia

Abstract

Cutaneous T-cell lymphomas are a heterogeneous group of T-cell lymphoproliferative diseases affecting the skin. Mycosis fungoides and Sezary syndrome are the most studied variants of them. The literature review includes the latest published data on the pathological processes development in mycosis fungoides and Sezary syndrome and the diagnosis of these diseases. The genomic instability features in cutaneous T-cell lymphomas are described, the existing hypotheses of the origin of these diseases are considered based on the results of T-cell receptor repertoire studying.

Publisher

Publishing House ABV Press

Subject

Oncology,Hematology

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