Affiliation:
1. N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Abstract
The objective of study is to estimate the efficiency of extracorporeal free light chains of immunoglobulin elimination in patients with monoclonal gammopathies (n = 12) during hemodialysis using selective filters.Materials and methods. A blood and dialysate free light chains concentrations change was criterion of efficiency.Results and conclusion. The selective free light chains filtration give the possibility of an adequate anti-tumor therapy, could prevent the development of irreversible renal failure and hypoalbuminemia.
Publisher
Publishing House ABV Press
Reference13 articles.
1. Lubimova N.V., Turko T.A., Votyakova O.M., Kushlinskiy N.E. Serum immunoglobulin free light chains in patients with monoclonal gammopathies. Bulleten eksperimentalnoy biologii i meditsiny = Bulletin of Experimental Biology and Medicine 2012;153(2):217–22. (In Russ.).
2. Turko T.A., Lubimova N.V., Ageeva T.V., Votyakova O.M. Free light chains of immunoglobulins in the diagnosis and prognosis of multiple myeloma. Klinicheskaya laboratornaya diagnostika = Clinical Laboratory Diagnostics 2010;(9):29. (In Russ.).
3. Hutchison C.A., Cockwell P., Reid K. et al. Efficient removal of immunoglobuline free light chains by hemodialysis for multiple myeloma: in vitro and in vivo stydies. J Am Soc Nephrol 2007;18(3): 886–95. DOI: 10.1681/ASN.2006080821.
4. Iggo N., Winearls C.G., Davies D.R. The development of cast-nephropathy in multiple myeloma. QJM 1997;90(11):653–6.
5. Knudsen L.M., Hjorth M., Hippe E. Renal failure in multiple myeloma: reversibility and impact on prognosis. Eur J Haematol 2000;65(3):175–81.
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