Clinical and morphological features, immune profile of renal cell tumors with clear cytoplasm

Author:

Osmanov Yu. I.1ORCID,Kogan E. A.2ORCID,Severgina L. O.2ORCID,Rapoport L. M.3ORCID,Aleksandrov N. S.2ORCID,Tsarichenko D. G.3ORCID,Korolyov D. O.3ORCID

Affiliation:

1. Sechenov First Moscow State Medical University, Ministry of Health of Russia; Scientific Clinical Center, Russian Railway

2. Sechenov First Moscow State Medical University, Ministry of Health of Russia

3. Institute for Urology and Reproductive Health, Sechenov First Moscow State Medical University, Ministry of Health of Russia

Abstract

In the structure of oncological morbidity, renal cell carcinoma takes the 10th place among malignant neoplasms. The increase in incidence is observed from the age of 35–40 years and reaches a maximum at the age of 65–70 years. In terms of frequency of occurrence, clear cell renal cell carcinoma is ranked first among all kidney tumors. Meanwhile, due to the high heterogeneity of renal cell carcinomas with clear cytoplasm group, significant differential diagnostic difficulties arise in the morphological verification of these tumors. The article presents all nosological forms of kidney tumors with clear cytoplasm and provides a database of already known immunohistochemical markers for each nosological unit.

Publisher

Publishing House ABV Press

Subject

Urology,Nephrology,Radiology Nuclear Medicine and imaging,Oncology,Surgery

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