Iron metabolism, ferroptosis and cancer-Reference-Cited by-同舟云学术

Iron metabolism, ferroptosis and cancer

Published:2017-09-30 Issue:3 Volume:16 Page:14-20
ISSN:1726-9784
Container-title:Russian Journal of Biotherapy
language:
Short-container-title:Rossijskij bioterapevtičeskij žurnal

Author:

Vartanian A. A.¹

Affiliation:

1. N.N. Blokhin Russian Cancer Research Center

Abstract

In 2012 the new, iron-dependent form of cell death - ferroptosis - distinct from apoptosis, autophagy and programmed necrosis at morphological, biochemical, and genetic levels has been described. In this review we will discuss the iron metabolism in physiological and pathological processes in humans, the molecular characteristics of ferroptosis and therapeutic options of cancer patients in the light of new data.

Publisher

Publishing House ABV Press

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