Partial and complete spontaneous regression of testicular seminoma: clinical cases-Reference-Cited by-同舟云学术

Partial and complete spontaneous regression of testicular seminoma: clinical cases

Published:2022-08-14 Issue:2 Volume:18 Page:198-205
ISSN:1996-1812
Container-title:Cancer Urology
language:
Short-container-title:Onkourologiâ

Author:

Surkova V. S.¹^ORCID,Volchenko N. N.¹^ORCID,Burakova V. A.¹^ORCID,Lavrova A. M.¹^ORCID,Ashirova F. S.²^ORCID,Khakimova G. G.³^ORCID

Affiliation:

1. P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia

2. P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

3. Tashkent City Branch, Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology; Department of Oncology, Pediatric Oncology, Tashkent Pediatric Medical Institute

Abstract

Spontaneous tumour regression is a rare phenomenon in which there is a complete or partial regression of the primary tumour, clinically manifested by metastatic lesions. We report a case of a 34-year-old male with partial spontaneous regression of testicular seminoma detected by a supraclavicular lymph node biopsy. He underwent inguinal orchifunicolectomy. Based on the results of histological examination, against the background of multiple complexes of intratubular germ cell neoplasia in situ, foci of invasive growth and involution were identified, indicating a spontaneously regressing testicular tumour. We report the second case of a 52-year-old male with total spontaneous regression of testicular seminoma detected by a spermatic cord biopsy. Based on the results of histological examination, against fibrosis and proliferation of Leydig cells, there are atrophy of seminiferous tubules and complexes of intratubular germ cell neoplasia in situ in part of them.

Publisher

Publishing House ABV Press

Subject

Urology,Nephrology,Radiology, Nuclear Medicine and imaging,Oncology,Surgery

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