Author:
Vasilyev A. V.,Govorov A. V.,Shiryaev A. A.,Sukhikh S. O.,Zherdev A. A.,Shakurov A. V.,Pushkarev А. V.,Tsiganov D. I.,Pushkar D. Yu.
Abstract
Focal therapy is a promising option for localized prostate cancer treatment in low and intermediate risk patients. The combination of minimal invasiveness, disease control and the possibility of re-treatment in case of recurrence have significantly increased interest in focal therapy. However, before the final introduction of focal therapy into clinical practice, a number of significant limitations have yet to be overcome, such as patient selection, visualization of target, the choice of the treatment modality and the surgery planning, as well as the development of a follow-up protocol. Studies have shown that focal therapy has minimal impact on the quality of life, but its oncological effectiveness has yet to be evaluated in comparison with radical methods of treatment.
Publisher
Publishing House ABV Press
Subject
Urology,Nephrology,Radiology, Nuclear Medicine and imaging,Oncology,Surgery
Reference27 articles.
1. Zlokachestvennye novoobrazovaniya v Rossii v 2015 godu (zabolevaemost' i smertnost'). Pod red. A.D. Kaprina, V.V. Starinskogo, G.V. Petrovoi. M.: MNIOI im. P.A. Gertsena – filial FGBU «NMIRTs» Minzdrava Rossii, 2017. 250 s. [Malignant tumors in Russia in 2015 (morbidity and fatality). Eds.: A.D. Kaprin, V.V. Starinskiy, G.V. Petrova. Moscow: MNIOI im. P.A. Gertsena – filial FGBU “NMIRTS” Minzdrava Rossii, 2017. 250 p. (In Russ.)].
2. Murphy D.G., Walton T.J., Connolly S., Costello A.J. Focal therapy for localised prostate cancer: are we asking the correct research questions? BJU Int 2012;109(1):1–3. DOI: 10.1111/j.1464-410X.2011.10804.x. PMID: 22151749.
3. Bott S.R., Ahmed H.U., Hindley R.G. et al. The index lesion and focal therapy: an analysis of the pathological characteristics of prostate cancer. BJU Int 2010;106(11): 1607–11. DOI: 10.1111/j.1464-410X.2010.09436.x. PMID: 20553262.
4. Futterer J.J., Briganti A., De Visschere P. et al. Can clinically significant prostate cancer be detected with multiparametric magnetic resonance imaging? A systematic review of the literature. Eur Urol 2015;68(6):1045–53. DOI: 10.1016/j.eururo.2015.01.013. PMID: 25656808.
5. Liu W., Laitinen S., Khan S. et al. Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat Med 2009;15(5):559–65. DOI: 10.1038/nm.1944. PMID: 19363497.
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