Outcomes of neuroinfections and their predictors

Author:

Morozova E. A.1,Ertakhova M. L.2ORCID

Affiliation:

1. Chair of Children’s Neurology, Kazan State Medical Academy

2. Republican Children’s Clinical Hospital, Ministry of Health of the Udmurt Republic

Abstract

Despite the success of vaccine prophylaxis and therapy, neuroinfections remain a serious problem due to the epidemic threat, high mortality and residual disabling and maladaptive neurological deficits in half of the cases.The aim of the literature review was to study modern publications concerning the dynamics of the infectious process in the central nervous system, the nature and predictors of its outcome in children.The results confirmed the effectiveness of social modification with the help of vaccination, guidelines and increased availability of medical care, leading to a decrease in mortality and morbidity of vaccine-controlled neuroinfections. At the same time, the general morbidity and due to the severity of complications and structural acute phase defect post-infectious neurological deficit in the form of epilepsy, motor, cognitive and behavioral disorders remain the same.The study of the outcomes of neuroinfections, their clinic and treatment at all stages, including the remote one, is necessary to develop an optimal protocol for the treatment and rehabilitation of children who have undergone meningitis and encephalitis in order to improve their quality of life.

Publisher

Publishing House ABV Press

Subject

Clinical Neurology,Pediatrics, Perinatology, and Child Health

Reference38 articles.

1. Karlov V.A., Morozova E.A., Ratner F.L. et al. Peculiarities of epilepsy and cognitive disorders in children with perinatal pathology of the brain. Psikhicheskoe zdorovye = Mental Health 2017;15(1):29– 37. (In Russ.).

2. Morozova E.A., Sergeeva R.R., Morozov D.V. Predictors of neonatal seizures development in children with perinatal brain pathology. Prakticheskaya meditsina = Practical Medicine 2019;7(17):117–20. (In Russ.). DOI: 10.32000/2072-1757-2019-7-117-120.

3. Samoilova I.G. Medical rehabilitation of children after neuroinfections: organizational approaches. Zhurnal infektologii = Journal Infectology 2017;9(1):104–6. (In Russ.). DOI: 10.22625/2072-6732.

4. Samoilova I.G. Economic efficiency of rehabilitation of children after neuroinfection. Vyatskiy meditsinskiy vestnik = Vyatskiy Medical Annals 2019;(1):64–6. (In Russ.).

5. Skripchenko N.V., Ivanova M.V., Vilnits A.A. et al. Neuroinfections in children: Tendencies and prospects. Rossiyskiy vestnik perinatologii i pediatrii = Russian Bulletin of Perinatology and Pediatrics 2016;(4):9–22. (In Russ.). DOI: 10.21508/1027-4065.

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