Complications after endoprosthetic reconstruction for the tumor around the knee in children and adolescents

Abstract

The objective: аnalysis of complications after endoprosthetic reconstruction in children and adolescents according to the Henderson classification of failure of limb salvage surgery modified by the International Society of Limb Salvage committee (ISOLS).Materials and methods.This study evaluates complications rates and mode of failures after endoprosthetic reconstruction for the tumor around the knee in 97 patients treated from 2012 to 2018 in D. Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology.Results. Overall  19,6 %  of  failures  were  identified.  The  most  common  postoperative  complications  were  structural failu res, infection and soft-tissue failure (6,19; 5,15 and 3,1 % respectively). None of the developed failures affected the timing of treatment protocol.Conclusion. Literature  review  and  the  study  results  demonstrate  that  higher  risk  of  failure  in  the  paediatric  group of patients is attributed to deficiency of adjacent soft-tissue and bone, skeletal immaturity, using of expandable endoprostheses and increased patient activity at this age. Multicenter studies are needed to optimize prevention and management of failures after endoprosthetic reconstruction.