The effect of antibiotics on spermatogenesis (review)-Reference-Cited by-同舟云学术

The effect of antibiotics on spermatogenesis (review)

Published:2021-02-12 Issue:4 Volume:21 Page:40-46
ISSN:2412-8902
Container-title:Andrology and Genital Surgery
language:
Short-container-title:Androl. genit. hir.

Author:

Kadyrov Z. A.¹^ORCID,Akramov M. M.¹,Aldyrakov E. M.¹

Affiliation:

1. RUDN University

Abstract

This review analyzes studies on the negative effects of antibiotics on reproductive organs and their function. Many experimental studies record the negative effect of certain antibiotics, depending on the dose applied, on spermatogenesis. Unlike drugs of other groups, in which a direct cytotoxic effect on the testicular tissue occurs through a change in the level of hormones of the hypothalamic-pituitary-gonadal axis or through a direct effect on the testicle itself, when using some antibiotics, most often against the background of the inflammatory process, oxidative stress occurs in the testicular tissues, which leads to dystrophic lesions and violations of spermatogenesis indicators.

Publisher

Publishing House ABV Press

Subject

Urology,Reproductive Medicine,Surgery

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