Primary Ewing sarcoma of the sphenoid bone with infrasellar spread in a 17-year-old patient: case report and literature review-Reference-Cited by-同舟云学术

Primary Ewing sarcoma of the sphenoid bone with infrasellar spread in a 17-year-old patient: case report and literature review

Published:2021-08-28 Issue:2 Volume:13 Page:26-35
ISSN:2782-3687
Container-title:Bone and soft tissue sarcomas, tumors of the skin
language:
Short-container-title:jour

Author:

Kutin M. A.¹^ORCID,Ivanov V. V.²^ORCID,Kalinin P. L.¹^ORCID

Affiliation:

1. N.N. Burdenko National Medical Research Center of Neurosurgery, Ministry of Health of Russia

2. Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia

Abstract

We performed retrospective analysis of publications describing cases of Ewing sarcoma of the skull base with exceedingly rare locations (including the area of the sphenoid bone, its wings, sinus, and adjacent structures). Ewing sarcoma is usually diagnosed in children. The peak incidence is registered in patients aged 10–15 years, whereas adults and children under 5 years of age are very unlikely to develop this disease. In this article, we also report a case of Ewing sarcoma of the skull bones affecting the sphenoid bone and sphenoid sinus. The patient has undergone surgery followed by chemoradiotherapy. High invasion potential (tumor spread in several directions), high malignancy, and compression of the adjacent structures of the brain make the analysis of Ewing sarcoma located in areas that cannot be easily approached particularly interesting for neurosurgeons, since surgery is the main treatment option for such patients.

Publisher

Publishing House ABV Press

Reference25 articles.

1. Güzel A., Tatli M., Er U. et al. Multifocal Ewing’s sarcoma of the brain, calvarium, leptomeninges, spine and other bones in a child. J Clin Neurosci 2008;15(7):813–7. DOI: 10.1016/j.jocn.2006.09.009.

2. Cugati G., Singh M., Pande A. et al. Isolated skull base primary Ewing’s sarcoma: an extremely rare location. J Cancer Res Ther 2013;9(4):741–2. DOI: 10.4103/0973-1482.126479.

3. Desai K.I., Nadkarni T.D., Goel A. et al. Primary Ewing’s sarcoma of the cranium. Neurosurgery 2000;46(1):62–9.

4. Agrawal A., Dulani R., Mahadevan A. et al. Primary Ewing’s sarcoma of the frontal bone with intracranial extension. J Cancer Res Ther 2009;5(3):208–9. DOI: 10.4103/0973-1482.57129.

5. Bricha M., Jroundi L., Boujida N. [Primary Ewing sarcoma of the skull vault] J Radiol 2007;88(12):1899–901. (In French.) DOI: 10.1016/s0221-0363(07)78370-1.