Noninvasive colorectal cancer screening techniques: literature review-Reference-Cited by-同舟云学术

Noninvasive colorectal cancer screening techniques: literature review

Published:2023-09-20 Issue:3 Volume:3 Page:57-63
ISSN:2782-6171
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Author:

Vereshchak V. V.¹^ORCID,Iurichev I. N.¹^ORCID,Rasulov A. O.¹^ORCID,Madyarov J. M.¹^ORCID

Affiliation:

1. Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

Abstract

Fecal DNA testing is a noninvasive method recommended by professional medical societies for colorectal cancer screening in individuals with intermediate risk of the disease. Adenamatous and serrated lesions, as well as cancer, lead to exfoliation of cells containing neoplastic altered DNA which, in turn, can be detected with sensitive testing methods aimed at specific genetic and epigenetic biomarkers. Mt-sDNA test approved by the United States Food and Drug Administration in 2014 showed sensitivity of 92 % for detection of colorectal cancer which is much higher than sensitivity of fecal immunochemical test (74 %).

Publisher

Publishing House ABV Press

Reference30 articles.

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