Case report: role of multidisciplinary approach in a case of spine osteosarcoma with oligometastatic heart disease

Author:

Tararykova A. A.1ORCID,Valiev A. K.1ORCID,Kononets P. V.1ORCID,Charchyan E. R.2ORCID,Kabardaev R. M.1ORCID,Fedorova A. V.1ORCID,Batyrova G. S.1ORCID,Shin A. R.1ORCID,Kozlov N. A.1ORCID

Affiliation:

1. N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

2. B.V. Petrovsky Russian Surgery Research Center

Abstract

Introduction. Primary spinal osteosarcoma and rare metastatic heart lesion are considered significant factors for poor prognosis. The available work indicates that combined treatment, including the radical surgery of heart solitary metastatic lesion, probably provides the best outcome.Case report. Man, 27-year-old, with Th8 spinal osteosarcoma and solitary left atrial metastasis. From October 2019 to February 2020 5 cycles of chemotherapy (high doses of platinum and doxorubicin) were carried out with positive effect. Next steps were surgery: March 2020 – spondylectomy of the Th8 vertebra with combined stabilization; September 2020 – subtotal resection with plasty of the right atrium, tricuspid valve and prosthesis of the right coronary artery. Between the first and second surgery, 4 more same chemotherapy cycles were carried out. Currently, 24 months after completion of treatment, there are no signs of the disease.Conclusion. The article presents a unique case of treatment of primary osteosarcoma and metastatic lesion of rare location. Multidisciplinary approach and combination treatment in specialized centers increase the probability of favorable outcome in such cases.

Publisher

Publishing House ABV Press

Reference16 articles.

1. Katonis P., Datsis G., Karantanas A. et al. Spinal osteosarcoma. Clin Med Insights Oncol 2013;7:199–208. DOI: 10.4137/CMO.S10099

2. Bishop M.W., Chang Y.C., Krailo M.D. et al. Assessing the prognostic significance of histologic response in osteosarcoma: a comparison of outcomes on CCG-782 and INT0133-A report from the Children’s Oncology Group Bone Tumor Committee. Pediatr Blood Cancer 2016;63(10):1737–43. DOI: 10.1002/pbc.26034

3. SEER Preliminary Cancer Incidence Rate Estimates for 2017, and diagnosis years 2000 to 2017, SEER 18. Available by: https://seer.cancer.gov/statistics/preliminary-estimates/.

4. Malignant neoplasms in Russia in 2020 (morbidity and mortality). Ed. by A.D. Kaprin, V.V. Starinsky, A.O. Shakhzadova. P.A. Herzen Institute of Medical Research – branch of the Federal State Budgetary Institution “NMIC of Radiology” of the Ministry of Health of Russia, 2021. 252 p. (In Russ.).

5. Salah S., Ahmad R., Sultan I. et al. Osteosarcoma with metastasis at initial diagnosis: current outcomes and prognostic factors in the context of a comprehensive cancer center. Mol Clin Oncol 2014;2(5):811–6. DOI: 10.3892/mco.2014.325

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3