Embryotoxic and Teratogenic Effects of Gamma Radiation on Zebrafish (Danio rerio)-Reference-Cited by-同舟云学术

Embryotoxic and Teratogenic Effects of Gamma Radiation on Zebrafish (Danio rerio)

Published:2021-04-27 Issue:6 Volume:65 Page:11-16
ISSN:1024-6177
Container-title:Medical Radiology and radiation safety
language:en
Short-container-title:

Author:

Isaev D¹,Guryev D.²³,Blohina T.⁴,Yashkina E.,Osipov A.⁴

Affiliation:

1. A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia

2. A.I. Burnasyan Federal Medical Biophysical Center of FMBA

3. N.N. Semenov Institute of Chemical Physics

4. A.I. Burnasyan Federal Medical Biophysical Center (FMBC) FMBA

Abstract

The review considers investigations presenting experimental data on the embryotoxic and teratogenic effects of exposure to ionizing radiation in zebrafish (Danio rerio) which is a convenient model for experimental embryology and radiation biology. The molecular mechanisms involved in response to the ionizing radiation influence as well as determining the embryonic death level, development disorders of embryos are examined. The data on acute and chronic effects of ionizing radiation on embryos of various stages of development with wide range of dose rates are presented. It was shown that the influence of γ-radiation on the death and development of zebrafish embryos is nonmonotonic and depends both on the irradiation conditions and on the stage of embryogenesis. The results of such studies are extremely important for understanding the mechanisms of radiation-induced biological effects formation in the embryogenesis of vertebrates, including humans, as well as for developing methods and approaches to assessing radiation risk for a developing organism.

Publisher

Infra-M Academic Publishing House

Subject

Nuclear Energy and Engineering

Reference40 articles.

1. Assessment of risk from low-level exposure to radiation and chemicals. A critical overview. Basic Life Sci. 1985;33:1-529., Assessment of risk from low-level exposure to radiation and chemicals. A critical overview. Basic Life Sci. 1985;33:1-529.

2. Radiation cancer analysis and low dose risk assessment: new developments and perspectives. Proceeding of the 20th LH Gray Conference. February 17-21, 2002. Ede, The Netherlands. J Radiol Prot. 2002;22(3A):A1-185., Radiation cancer analysis and low dose risk assessment: new developments and perspectives. Proceeding of the 20th LH Gray Conference. February 17-21, 2002. Ede, The Netherlands. J Radiol Prot. 2002;22(3A):A1-185.

3. Ionising radiation quality, molecular mechanisms, cellular effects, and their consequences for low level risk assessment and radiation therapy. Proceedings of the 14th International Symposium on microdosimetry. November 12-18, 2005. Venezia, Italy. Radiat Prot Dosimetry. 2006;122(1-4):1-550., Ionising radiation quality, molecular mechanisms, cellular effects, and their consequences for low level risk assessment and radiation therapy. Proceedings of the 14th International Symposium on microdosimetry. November 12-18, 2005. Venezia, Italy. Radiat Prot Dosimetry. 2006;122(1-4):1-550.

4. Sample BE. Overview of exposure to and effects from radionuclides in terrestrial and marine environments. Integr Environ Assess Manag. 2011;7(3):368-70. DOI: 10.1002/ieam.239., Sample BE. Overview of exposure to and effects from radionuclides in terrestrial and marine environments. Integr Environ Assess Manag. 2011;7(3):368-70. DOI: 10.1002/ieam.239.

5. Vives i Batlle J, Balonov M, Beaugelin-Seiller K, Beresford NA, Brown J, Cheng JJ, et al. Inter-comparison of absorbed dose rates for non-human biota. Radiat Environ Biophys. 2007;46(4):349-73. DOI: 10.1007/s00411-007-0124-1., Vives i Batlle J, Balonov M, Beaugelin-Seiller K, Beresford NA, Brown J, Cheng JJ, et al. Inter-comparison of absorbed dose rates for non-human biota. Radiat Environ Biophys. 2007;46(4):349-73. DOI: 10.1007/s00411-007-0124-1.