Evaluation of the SPECT/CT Method in the Diagnosis of Ochronosis. Clinical Case-Reference-Cited by-同舟云学术

Evaluation of the SPECT/CT Method in the Diagnosis of Ochronosis. Clinical Case

Published:2020-04-29 Issue:2 Volume:65 Page:82-86
ISSN:1024-6177
Container-title:Medical Radiology and radiation safety
language:en
Short-container-title:

Author:

Ryzhkov A.¹,Krylov A.¹,Bludov A.¹,Kuzin A.²,Kaspshik S.¹,Dolgushin M.¹

Affiliation:

1. N.N. Blokhin National Medical Research Center of Oncology

2. Russian Medical Academy of Continuous Professional Education

Abstract

Purpose: Is to demonstrate functional and structural changes in the musculoskeletal system of the patient with ochronosis using bone scan and hybrid imaging consisting of single-photon emission computed tomography (SPECT) and X-ray transmission computed tomography (CT) scan (SPECT/CT). Material and methods: A clinical case report of patient with ochronosis, examined with bone scan and SPECT/CT. Results: In this article we show a clinical case with the picture of mineral metabolism disorder and severe degenerative changes of musculoskeletal system in patient with ochronosis (a genetically determined disease), caused by metabolic disorders of homogentisic acid. We used hybrid SPECT/CT method for evaluation of this disease. Conclusion: SPECT/CT method demonstrated structural and metabolic changes. This method allowed us to reveal the specific changes in cases of ochronosis, but also it shows the possibility of using radionuclide methods in solving non-standard situations, while this method has not previously been applied.

Publisher

Infra-M Academic Publishing House

Subject

Nuclear Energy and Engineering

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