An Effective Method of Simulation for the Leksell Gamma Knife Perfexion by Rotating Particles in the Phase Space File

Author:

Medjadj T.1,Ksenofontov A.1,Dalechina A.2

Affiliation:

1. National Research Nuclear University MEPhI

2. Neurosurgery Business Center, Moscow GammaKnife Center

Abstract

Purpose: To develop an effective method of Monte Carlo simulation of the GammaKnife Perfexion system by rotating particles in the phase space file (PSF). This method does not require simulating of all 192 sources that are distributed in the conical form of the Perfexion collimator. The simulation was performed only for 5 out of 192 sources for each collimator size. Material and methods: Monte Carlo simulation of dose distribution for previous models of GammaKnife system requires phase space file for only one source, since this phase space is identical for all the 201 sources. The Perfexion model is more complex due to the non-coaxial positions of the sources and the complexity of the collimator system itself. In this work, we present an effective method to simulate the Perfexion model using a phase space file. Penelope Monte Carlo code was used to perform this simulation. In this method, the PSF was obtained for one source in each ring, resulting in five files for each collimator size. PSF for other sources were created by azimuthal redistribution of particles, in the obtained PSF, by rotation around the Z-axis. The phase space files of the same ring were then stored together in a single file. Results: The paper presented MC simulation using the azimuthal redistribution of particles in the phase space file by rotation around the Z-axis. The simulation has been validated comparing the dose profiles and output factors with the data of the algorithm TMR10 planning system Leksell Gamma Plan (LGP) in a homogeneous environment. The acceptance criterion between TMR10 and Monte Carlo calculations for the profiles was based on the gamma index (GI). Index values more than one were not detected in all cases, which indicates a good agreement of results. The differences between the output factors obtained in this work and the TMR10 data for collimators 8 mm and 4 mm are 0.74 and 0.73 %, respectively. Conclusion: In this work successfully implemented an effective method of simulating the Leksell Gamma knife Perfexion system. The presented method does not require modeling for all 192 sources distributed in the conical form of the Perfexion collimator. The simulation was performed for only five sources for each collimator and their files PSF were obtained. These files were used to create the PSF files for other sources by azimuthal redistribution of particles, in these files, by rotation around the Z-axis providing correct calculations of dose distributions in a homogeneous medium for 16, 8 and 4 mm collimators.

Publisher

Infra-M Academic Publishing House

Subject

Nuclear Energy and Engineering

Reference10 articles.

1. Maitz A, Flickinger J, Lunsford L. Gamma Knife Technology and Physics: Past, Present, and Future. Lunsford LD, Kondziolka D, Flickinger JC (eds): Gamma Knife Brain Surgery. Prog Neurol Surg. Basel, Karger. 1998;14:5-20., Maitz A, Flickinger J, Lunsford L. Gamma Knife Technology and Physics: Past, Present, and Future. Lunsford LD, Kondziolka D, Flickinger JC (eds): Gamma Knife Brain Surgery. Prog Neurol Surg. Basel, Karger. 1998;14:5-20.

2. Голанова АВ, Костюченко ВВ. Нейрорадиохирургия на Гамма-Ноже. В сб.: История стереотаксиса и радиохирургии. ред. Костюченко ВВ. – Москва, 2018;121-31. [Golanov AV, Kostjuchenko BB. Neuroradiosurgery with Gamma Knife. In: History of Stereoraxy and Radiosurgery. Kostjuchenko BB, ed. Moscow. 2018:121-31. (In Russ.)]., Golanov AV, Kostjuchenko BB. Neuroradiosurgery with Gamma Knife. In: History of Stereoraxy and Radiosurgery. Kostjuchenko BB, ed. Moscow. 2018:121-31. (In Russ.)

3. Yuan J, Lo SS, Zheng Y, Sohn JW, Sloan AE, Ellis R, et al. Development of A Monte Carlo Model for Treatment Planning Dose Verification of the Leksell Gamma Knife Perfexion Radiosurgery System. J Applied Clinical Medical Physics. 2016;17(4):190–201., Yuan J, Lo SS, Zheng Y, Sohn JW, Sloan AE, Ellis R, et al. Development of A Monte Carlo Model for Treatment Planning Dose Verification of the Leksell Gamma Knife Perfexion Radiosurgery System. J Applied Clinical Medical Physics. 2016;17(4):190–201.

4. Lindquist C, Paddick I. The Leksell Gamma Knife Perfexion and Comparisons with Its Predecessors. Neurosurgery. 2007;61:130-40., Lindquist C, Paddick I. The Leksell Gamma Knife Perfexion and Comparisons with Its Predecessors. Neurosurgery. 2007;61:130-40.

5. Ma L, Kjäll P, Novotny J, Nordström H, Johansson J, Verhey L. A Simple and Effective Method for Validation and Measurement of Collimator Output Factors for Leksell Gamma Knife Perfexion. Phys Med Biol. 2009;54:3897-907., Ma L, Kjäll P, Novotny J, Nordström H, Johansson J, Verhey L. A Simple and Effective Method for Validation and Measurement of Collimator Output Factors for Leksell Gamma Knife Perfexion. Phys Med Biol. 2009;54:3897-907.

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3