Analysis of the efficiency of the application of cell therapy for local radiation injurie-Reference-Cited by-同舟云学术

Analysis of the efficiency of the application of cell therapy for local radiation injurie

Published:2021-05-25 Issue:1 Volume:66 Page:69-78
ISSN:1024-6177
Container-title:Medical Radiology and radiation safety
language:en
Short-container-title:

Author:

Brunchukov V.¹,Astrelina T.¹,Samoylov A.²

Affiliation:

1. A.I. Burnasyan Federal Medical Biophysical Center (FMBC) FMBA

2. A.I. Burnasyan Federal Medical Biophysical Center of FMBA

Abstract

Every year the proportion of radiation therapy as an independent method of radical treatment of cancer patients is increasing. Exposure to radiation as a result of medical treatment can lead to the development in patients of local radiation injuries (LRJ) (radiation reactions) on the skin and surrounding tissues. Today, there is no standard treatment for LRJ, known methods are ineffective In this regard, research aimed at finding effective methods of treatment leading to accelerated wound healing, a decrease in inflammation and a decrease in fibrosis is relevant. In recent years, there has been an active study of the effectiveness of the use of cell therapy, including mesenchymal stem cells, their cell products, minimally manipulated cell products, etc., in complex therapy for local radiation injuries. In the presented literature review, the effectiveness of the use of cellular products in local radiation damage to the skin caused by sources of ionizing radiation is considered. Bibliographic searches of works were carried out on the basis of the PubMed portal, published in the period from 2015 to August 2020.

Publisher

Infra-M Academic Publishing House

Subject

Nuclear Energy and Engineering

Reference75 articles.

1. Tarkhanov IR. Experiments on the effect of X-rays on an animal organism. - In the book: IR. Tarkhnishvili. Selected Works. - Tbilisi: Sabchota Sakartvelo, 1961:324-31(In Russian)., Tarkhanov IR. Experiments on the effect of X-rays on an animal organism. - In the book: IR. Tarkhnishvili. Selected Works. - Tbilisi: Sabchota Sakartvelo, 1961:324-31(In Russian).

2. Kapustinskaya KA Henri Becquerel. M .: Atomizdat, 1965:59-60:84 (In Russian)., Kapustinskaya KA Henri Becquerel. M .: Atomizdat, 1965:59-60:84 (In Russian).

3. Bayurov LI Radiobiology: textbook. Krasnodar: KubGAU, 2008:331 (In Russian)., Bayurov LI Radiobiology: textbook. Krasnodar: KubGAU, 2008:331 (In Russian).

4. Sources and effects of ionizing radiation : UNSCEAR 2008… rep. to the General assembly, V.-2 -with sci. ann. / U.N. Sci. comm. on the effects of atomic radiation. New York : U.N., 2011., Sources and effects of ionizing radiation : UNSCEAR 2008… rep. to the General assembly, V.-2 -with sci. ann. / U.N. Sci. comm. on the effects of atomic radiation. New York : U.N., 2011.

5. Grebenyuk AN, Strelova OYu, Legeza VI, Stepanova EN. Fundamentals of radiobiology and radiation medicine: a textbook. - SPb: LLC "FOLIANT Publishing House", 2012:232 (In Russian)., Grebenyuk AN, Strelova OYu, Legeza VI, Stepanova EN. Fundamentals of radiobiology and radiation medicine: a textbook. - SPb: LLC "FOLIANT Publishing House", 2012:232 (In Russian).