MORPHOFUNCTIONAL STATE OF PLACENTA UNDER MYCOPLASMA INFECTION-Reference-Cited by-同舟云学术

MORPHOFUNCTIONAL STATE OF PLACENTA UNDER MYCOPLASMA INFECTION

Published:2018-10-05 Issue:69 Volume:1 Page:43-49
ISSN:1998-5029
Container-title:Bulletin physiology and pathology of respiration
language:en
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Author:

Островская Ольга¹,Ostrovskaya Olga²,Ивахнишина Наталья,Ivakhnishina Natalya,Кожарская Ольга³,Kozharskaya Ol'ga⁴,Мусатов Денис,Musatov Denis,Обухова Виктория,Obuhova Viktoriya,Власова Марина⁵,Vlasova Marina²,Наговицына Елена,Nagovitsyna E,Супрун Стефания⁶,Suprun Stefaniya⁷,Евсеева Галина⁵,Evseeva Galina²,Лебедько Ольга¹,Lebedko Olga²

Affiliation:

1. НИИ охраны материнства и детства

2. Research Institute of Maternity and Childhood Protection

3. Перинатальный центр министерства здравоохранения Хабаровского края

4. Department of Perinatal Center of Khabarovsk Krai Ministry of Public Health

5. Научно-исследовательский институт охраны материнства и детства

6. Хабаровский филиал Дальневосточного научного центра физиологии и патологии дыхания – НИИ охраны материнства и детства

7. Khabarovsk Branch of Far-Eastern Scientific Center of Physiology and Pathology of Respiration – Research Institute of Maternity and Childhood Protection

Abstract

Literature data on the ethiopathogenetic role of Ureaplasma species, Mycoplasma hominis in the development of premature delivery is contradictory due to the fact that Mycoplasma may be part of the normal microflora of women of reproductive age. The article is aimed to reveal the peculiarities of morphofunctional state of the placentas infected with Mycoplasma. The placentas were obtained from women whose pregnancy ended prematurely. Morphological, histological and molecular genetic study of 34 placentas from maternity patients with premature delivery was performed. Molecular genetic study was carried out by real-time PCR. Ureaplasma spp. was detected as a part of mono- and mixed infections in a concentration of 10*2 to 10*6 GE/mL in 32.3% of cases. Mycoplasma hominis was detected in 23.5% of cases, in a concentration of 10*3 to 10*6 GE/mL. Inflammatory changes in the membranes and placenta were revealed in all cases of Ureaplasma spp. detection as a monoinfection regardless of the degree of bacterial load, which confirms the belief about the pathogenetic role of Ureaplasma spp. in the process of reproductive disorders formation.

Publisher

Far Eastern Scientific Center Of Physiology and Pathology of Respiration

Subject

General Medicine

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