The Lack of Hepatocyte Steatosis in Adult-onset Type II Citrullinemia Patients as Assessed by 7-year Interval Paired Biopsies

Author:

Suzuki Hiroyuki1,Kawamura Yusuke1,Kinowaki Keiichi2,Akuta Norio1,Kasuya Kayoko1,Fujiyama Shunichiro1,Sezaki Hitomi1,Hosaka Tetsuya1,Saitoh Satoshi1,Kobayashi Masahiro1,Kobayashi Mariko3,Arase Yasuji1,Ikeda Kenji1,Suzuki Fumitaka1,Suzuki Yoshiyuki1,Kumada Hiromitsu1

Affiliation:

1. Department of Hepatology, Toranomon Hospital, Japan

2. Department of Pathology, Toranomon Hospital, Japan

3. Department of Liver Research Laboratory, Toranomon Hospital, Japan

Publisher

Japanese Society of Internal Medicine

Subject

General Medicine,Internal Medicine

Reference20 articles.

1. 1. Saheki T, Kobayashi K, Iijima M, et al. Pathogenesis and pathophysiology of citrin (a mitochondrial aspartate glutamate carrier) deficiency. Metab Brain Dis 17: 335-346, 2002.

2. 2. Kogure T, Kondo Y, Kakazu E, et al. Three cases of adult-onset type II citrullinemia treated with different therapies: efficacy of sodium pyruvate and low-carbohydrate diet. Hepatol Res 44: 707-712, 2014.

3. 3. Nakamura M, Yazaki M, Kobayashi Y, et al. The characteristics of food intake in patients with type II citrullinemia. J Nutr Sci Vitaminol 57: 239-245, 2011.

4. 4. Ikeda S, Yazaki M, Takei Y, et al. Type II (adult onset) citrullinaemia: clinical pictures and the therapeutic effect of liver transplantation. J Neurol Neurosurg Psychiatry 71: 663-670, 2001.

5. 5. Kimura N, Kubo N, Narumi S, et al. Liver transplantation versus conservative treatment for adult-onset type II citrullinemia: our experience and a review of the literature. Transplant Proc 45: 3432-3437, 2013.

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