Large Solid-pseudopapillary Neoplasm of the Pancreas with Aberrant Protein Expression and Mutation of β-Catenin: A Case Report and Literature Review of the Distribution of β-Catenin Mutation

Author:

Kobayashi Takahiko12,Ozasa Mariko2,Miyashita Kencho2,Saga Akiyoshi2,Miwa Kimiaki2,Saito Makoto2,Morioka Masanobu2,Takeuchi Motoya2,Takenouchi Nobuo2,Yabiku Takashi2,Kanno Hiromi3,Yuzawa Sayaka3,Tanino Mishie3,Tanaka Shinya3,Kawakami Hiroshi1,Asaka Masahiro1,Sakamoto Naoya1

Affiliation:

1. Department of Gastroenterology, Hokkaido University, Graduate School of Medicine, Japan

2. Aiiku Hospital, Japan

3. Laboratory of Cancer Research, Department of Pathology, Hokkaido University, Graduate School of Medicine, Japan

Publisher

Japanese Society of Internal Medicine

Subject

General Medicine,Internal Medicine

Reference31 articles.

1. 1. Chakhachiro ZI, Zaatari G. Solid-pseudopapillary neoplasm: a pancreatic enigma. Arch Pathol Lab Med 133: 1989-1993, 2009.

2. 2. Santini D, Poli F, Lega S. Solid-papillary tumors of the pancreas: histopathology. JOP 7: 131-136, 2006.

3. 3. Adams AL, Siegal GP, Jhala NC. Solid pseudopapillary tumor of the pancreas: a review of salient clinical and pathologic features. Adv Anat Pathol 15: 39-45, 2008.

4. 4. Serra S, Chetty R. Revision 2: an immunohistochemical approach and evaluation of solid pseudopapillary tumour of the pancreas. J Clin Pathol 61: 1153-1159, 2008.

5. 5. Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 303: 1483-1487, 2004.

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