Metformin-associated Lactic Acidosis with Hypoglycemia during the COVID-19 Pandemic
Author:
Affiliation:
1. Department of Diabetes, Metabolism and Endocrinology, Osaka Police Hospital, Japan
Publisher
Japanese Society of Internal Medicine
Subject
General Medicine,Internal Medicine
Link
https://www.jstage.jst.go.jp/article/internalmedicine/61/15/61_9179-21/_pdf
Reference19 articles.
1. 1. American Diabetes Association. 9. Pharmacologic approaches to glycemic treatment: standards of medical care in diabetes - 2021. Diabetes Care 44: S111-S124, 2021.
2. 2. DeFronzo R, Fleming GA, Chen K, Bicsak TA. Metformin-associated lactic acidosis: current perspectives on causes and risk. Metabolism 65: 20-29, 2016.
3. 3. Owen MR, Doran E, Halestrap AP. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem J 348: 607-614, 2000.
4. 4. Hunter RW, Hughey CC, Lantier L, et al. Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase. Nat Med 24: 1395-1406, 2018.
5. 5. Miller RA, Chu Q, Xie J, Foretz M, Viollet B, Birnbaum MJ. Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP. Nature 494: 256-260, 2013.
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