Cross-reacting Material-positive Hemophilia A Diagnosed in a Patient with a Spontaneous Thigh Hemorrhage

Author:

Saito Tatsuya1,Mukae Jyunichi1,Nakamura Yosuke1,Inaba Hiroshi2,Nogami Keiji3,Koyama Takatoshi4,Fukutake Katsuyuki25,Yamamoto Koh1

Affiliation:

1. Department of Hematology, Yokohama City Red Cross Hospital, Japan

2. Department of Laboratory Medicine, Tokyo Medical University, Japan

3. Department of Pediatrics, Nara Medical University, Japan

4. Department of Hematology, Graduate School of Health Care Sciences, Tokyo Medical and Dental University, Japan

5. Department of Molecular Genetics of Coagulation Disorders, Tokyo Medical University, Japan

Publisher

Japanese Society of Internal Medicine

Subject

General Medicine,Internal Medicine

Reference14 articles.

1. 1. White GC II, Rosendaal F, Aledort LM, et al. Definitions in hemophilia. Recommendation of the scientific subcommittee on factor VIII and factor IX of the scientific and standardization committee of the International Society on Thrombosis and Hemostasis. Thromb Haemost 85: 560, 2001.

2. 2. Hoyer LW, Breckenridge RT. Immunologic studies of antihemophilic factor (AHF, factor VIII): cross-reacting material in a genetic variant of hemophilia A. Blood 32: 962-971, 1968.

3. 3. Denson KW, Biggs R, Haddon ME, Borrett R, Cobb K. Two types of haemophilia (A+ and A-): a study of 48 cases. Br J Haematol 17: 163-171, 1969.

4. 4. Nishino M, Nishino S, Sugimoto M, Shibata M, Tsuji S, Yoshioka A. Changes in factor VIII binding capacity of von Willbrand factor and factor VIII coagulant activity in two patients with type 2N von Willebrand disease after hemostatic treatment and during pregnancy. Int J Hematol 64: 127-134, 1996.

5. 5. Oldenburg J, Pavlova A. Discrepancy between one-stage and chromogenic factor VIII activity assay results can lead to misdiagnosis of haemophilia A phenotype. Hämostaseologie 30: 207-211, 2010.

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