Non-Islet Cell Tumor Hypoglycemia Is Caused by Big IGF-II in a Patient with a Carcinosarcoma of the Uterus
Author:
Affiliation:
1. Division of Diabetes and Metabolism, Department of Internal Medicine, Iwate Medical University, Japan
2. Department of Pathology, Iwate Medical University, Japan
3. Department of Medicine II, Tokyo Women's Medical University, Japan
Publisher
Japanese Society of Internal Medicine
Subject
General Medicine,Internal Medicine
Link
https://www.jstage.jst.go.jp/article/internalmedicine/54/24/54_54.4945/_pdf
Reference13 articles.
1. 1. Fukuda I, Hizuka N, Takano K, Asakawa-Yasumoto K, Shizume K, Demura H. Characterization of insulin-like growth factor II (IGF-II) and IGF binding proteins in patients with non-islet-cell tumor hypoglycemia. Endocr J 40: 111-119, 1993.
2. 2. Fukuda I, Hizuka N, Ishikawa Y, et al. Clinical features of insulin-like growth factor-II producing non-islet-cell tumor hypoglycemia. Growth Horm IGF Res 16: 211-216, 2006.
3. 3. Kojima G, Terada KY, Miki N, Miki K. Non-islet cell tumor hypoglycemia associated with recurrent carcinosarcoma of the ovary. Endocr Pract 19: e83-e87, 2013.
4. 4. Qiu Q, Basak A, Mbikay M, Tsang BK, Gruslin A. Role of pro-IGF-II processing by proprotein convertase 4 in human placental development. Proc Natl Acad Sci USA 102: 11047-11052, 2005.
5. 5. Hizuka N, Fukuda I, Takano K, Asakawa-Yasumoto K, Okubo Y, Demura H. Serum high molecular weight form of insulin-like growth factor II from patients with non-islet cell tumor hypoglycemia is O-glycosylated. J Clin Endocrinol Metab 83: 2875-2877, 1998.
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1. Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2;Communications Biology;2023-08-19
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3. Non-islet cell tumor hypoglycemia in a patient with uterine carcinosarcoma;Gynecologic Oncology Reports;2022-02
4. Insulin-like growth factor 2: a poor prognostic biomarker linked to racial disparity in women with uterine carcinosarcoma;Cancer Medicine;2018-02-18
5. Levels of glucose-regulatory hormones in patients with non-islet cell tumor hypoglycemia: including a review of the literature;Endocrine Journal;2017
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