Early Pathological JC Virus Lesions in a Patient without Any MRI-based Indications

Author:

Sanjo Nobuo1,Nose Yurie1,Miyamoto Shouhei1,Shishido-Hara Yukiko2,Saito Tatsuya3,Fukuda Tetsuya3,Yamamoto Kurara4,Kobayashi Daisuke4,Yokota Takanori1

Affiliation:

1. Department of Neurology and Neurological Science, Tokyo Medical and Dental University, Japan

2. Department of Anatomic Pathology, Tokyo Medical University, Japan

3. Department of Hematology, Tokyo Medical and Dental University, Japan

4. Department of Human Pathology, Tokyo Medical and Dental University, Japan

Publisher

Japanese Society of Internal Medicine

Subject

General Medicine,Internal Medicine

Reference10 articles.

1. 1. Shishido-Hara Y. Progressive multifocal leukoencephalopathy and promyelocytic leukemia nuclear bodies: a review of clinical, neuropathological, and virological aspects of JC virus-induced demyelinating disease. Acta Neuropathol 120: 403-417, 2010.

2. 2. Berger JR, Aksamit AJ, Clifford DB, et al. PML diagnostic criteria: consensus statement from the AAN Neuroinfectious Disease Section. Neurology 80: 1430-1438, 2013.

3. 3. Nakamichi K, Kurane I, Saijo M. Evaluation of a quantitative real-time PCR assay for the detection of JC polyomavirus DNA in cerebrospinal fluid without nucleic acid extraction. Jpn J Infect Dis 64: 211-216, 2011.

4. 4. White MK, Sariyer IK, Gordon J, et al. Diagnostic assays for polyomavirus JC and progressive multifocal leukoencephalopathy. Rev Med Virol 26: 102-114, 2016.

5. 5. Babi M-A, Pendlebury W, Braff S, Waheed W. JC virus PCR detection is not infallible: a fulminant case of progressive multifocal leukoencephalopathy with false-negative cerebrospinal fluid studies despite progressive clinical course and radiological findings. Case Rep Neurol Med 643216, 2015.

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