A Prospective Study of Neoadjuvant Gemcitabine Plus Nab-paclitaxel in Patients with Borderline-resectable Pancreatic Cancer

Author:

Okano Naohiro1,Matsuki Ryota2,Toki Masao3,Gondo Koichi3,Ochiai Kazushige3,Watanabe Shunsuke3,Tateishi Hidekatsu4,Kogure Masaharu2,Suzuki Yutaka2,Sugiyama Masanori5,Nagashima Fumio1,Shibahara Junji6,Sakamoto Yoshihiro2,Furuse Junji1

Affiliation:

1. Department of Medical Oncology, Kyorin University Faculty of Medicine, Japan

2. Department of Hepato-Biliary-Pancreatic Surgery, Kyorin University Hospital, Japan

3. Department of Gastroenterology and Hepatology, Kyorin University School of Medicine, Japan

4. Department of Radiology, Kyorin University Faculty of Medicine, Japan

5. Tokyo Rosai Hospital, Japan

6. Department of Pathology, Kyorin University Faculty of Medicine, Japan

Publisher

Japanese Society of Internal Medicine

Subject

General Medicine,Internal Medicine

Reference36 articles.

1. 1. Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2021. CA Cancer J Clin 71: 7-33, 2021.

2. 2. NCCN Clinical Practice Guidelines in Oncology. Pancreatic Adenocarcinoma. Version 2.2021 [Internet]. [cited 2021 Dec 16]. Available from: https://www.nccn.org/professionals/physician_gls/pdf/pancreatic.pdf

3. 3. Huang L, Jansen L, Balavarca Y, et al. Resection of pancreatic cancer in Europe and USA: an international large-scale study highlighting large variations. Gut 68: 130-139, 2019.

4. 4. Oettle H, Post S, Neuhaus P, et al. Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial. JAMA 297: 267-277, 2007.

5. 5. Neoptolemos JP, Palmer DH, Ghaneh P, et al. Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial. Lancet 389: 1011-1024, 2017.

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