Clinical Characteristics of Patients who Developed Hepatocellular Carcinoma after Hepatitis C Virus Eradication with Interferon Therapy: Current Status in Japan

Author:

Sato Akira1,Sata Michio2,Ikeda Kenji3,Kumada Takashi4,Izumi Namiki5,Asahina Yasuhiro5,Osaki Yukio6,Chayama Kazuaki7,Kaneko Shuichi8,Sakai Akito8,Onji Morikazu9,Hiasa Yoichi9,Omura Takumi10,Ozeki Itaru10,Yokosuka Osamu11,Shiina Shuichiro12,Itsubo Mariko13,Nishiguchi Shuhei14,Hirano Katsuharu15,Ide Tatsuya2,Sakisaka Shotaro16,Yamasaki Takahiro17,Hidaka Isao17,Tanaka Masatoshi18,Kim Soo Ryang19,Ichida Takafumi15

Affiliation:

1. Department of Gastroenterology, St. Marianna University School of Medicine, Yokohama Seibu Hospital, Japan

2. Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Japan

3. Department of Hepatology, Toranomon Hospital, Japan

4. Department of Gastroenterology, Ogaki Municipal Hospital, Japan

5. Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Japan

6. Department of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Japan

7. Department of Medical and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Science, Hiroshima University, Japan

8. Department of Gastroenterology, Graduate School of Medicine, Kanazawa University, Japan

9. Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Japan

10. Department of Gastroenterology, Sapporo Kosei General Hospital, Japan

11. Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Japan

12. Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Japan

13. Department of Gastroenterology and Hepatology, Jikei University School of Medicine, Japan

14. Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, Japan

15. Department of Hepatology and Gastroenterology, Juntendo Shizuoka Hospital, Japan

16. Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine, Japan

17. Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Japan

18. Department of Gastroenterology, Kurume University Medical Center, Japan

19. Department of Gastroenterology, Kobe Asahi Hospital, Japan

Publisher

Japanese Society of Internal Medicine

Subject

General Medicine,Internal Medicine

Reference32 articles.

1. 1. World Health Organization. Global Alert and Response (GAR): Hepatitis C. 2012. Accessed 27 May 2013. http://www.who.Int/mediacentre/factsheets/fs164/en/index.html

2. 2. Center for Cancer Control and Information Services, National Cancer Center, Japan. Cancer Statistics in Japan-2011. Accessed 27 May 2013. http://ganjoho.jp/pro/statistics/en/backnumber/2012_en.html

3. 3. Umemura T, Kiyosawa K. Epidemiology of hepatocellular carcinoma in Japan. Hepatol Res 37: S95-S100, 2007.

4. 4. Yoshida H, Shiratori Y, Moriyama M, et al. Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan. Ann Intern Med 131: 174-181, 1999.

5. 5. Ikeda K, Saitoh S, Suzuki Y, et al. Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients. J Hepatol 28: 930-938, 1998.

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