Brain Biopsy Is More Reliable than the DNA test for JC Virus in Cerebrospinal Fluid for the Diagnosis of Progressive Multifocal Leukoencephalopathy

Author:

Ikeda Junji1,Matsushima Akira1,Ishii Wataru1,Goto Tetuya2,Takahashi Kenta3,Nakamichi Kazuo4,Saijo Masayuki4,Sekijima Yoshiki1,Ikeda Shu-ichi1

Affiliation:

1. Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Japan

2. Department of Neurosurgery, Shinshu University School of Medicine, Japan

3. Department of Pathology, National Institute of Infectious Diseases, Japan

4. Division of Virology 1, National Institute of Infectious Diseases, Japan

Publisher

Japanese Society of Internal Medicine

Subject

General Medicine,Internal Medicine

Reference22 articles.

1. 1. Weissert R. Progressive multifocal leukoencephalopathy. J Neuroimmunol 231: 73-77, 2011.

2. 2. Tan CS, Koralnik IJ. Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis. Lancet Neurol 9: 425-437, 2010.

3. 3. Marshall LJ, Major EO. Molecular regulation of JC virus tropism: insights into potential therapeutic targets for progressive multifocal leukoencephalopathy. J Neuroimmune Pharmacol 5: 404-417, 2010.

4. 4. Nakamichi K, Mizusawa H, Yamada M, et al. Characteristics of progressive multifocal leukoencephalopathy clarified through internet-assisted laboratory surveillance in Japan. BMC Neurol 12: 121, 2012.

5. 5. Kleinschmidt-DeMasters BK, Tyler KL. Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis. N Engl J Med 353: 369-374, 2005.

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