A Case of Multiple Myeloma which Cells Gained Multiple Gene and Chromosome Aberrations and Changed Their Morphology to Plasmablastoid and Lymphoblastoid during Less Than Two Years Course
Author:
Affiliation:
1. Department of Hematology, Yokohama-Minami Kyosai Hospital
2. Department of Hematopoietic Cell Transplantation, Yokohama-Minami Kyosai Hospital
3. Department of Hematology, Nippon Medical School
Publisher
Japanese Society of Internal Medicine
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/naika/101/11/101_3236/_pdf
Reference8 articles.
1. 1) Kumar SK, et al: Improved survival in multiple myeloma and the impact of novel therapies. Blood 111: 2516-2520, 2008.
2. 2) Neri A, et al: p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy. Blood 81: 128-135, 1993.
3. 3) Tiedemann RE, et al: Genetic aberrations and survival in plasma cell leukemia. Leukemia 22: 1044-1052, 2008.
4. 4) Jimenez-Zepeda VH, et al: Plasma cell leukemia: a highly aggressive monoclonal gammopathy with a very poor prognosis. Int J Hematol 89: 259-268, 2009.
5. 5) Terpos E, et al: Clinical implications of chromosomal abnormalities in multiple myeloma. Leuk Lymphoma 47: 803-814, 2006.
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