3) Metformin and Imeglimin -Similar Yet Different-
Author:
Affiliation:
1. Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine
Publisher
Japanese Society of Internal Medicine
Link
https://www.jstage.jst.go.jp/article/naika/112/9/112_1607/_pdf
Reference16 articles.
1. 1) Hallakou-Bozec S, et al: Mechanism of action of Imeglimin: A novel therapeutic agent for type 2 diabetes. Diabetes Obes Metab 23: 664-673, 2021.
2. 2) Theurey P, et al: Reduced lactic acidosis risk with Imeglimin: Comparison with Metformin. Physiol Rep 10: e15151, 2022.
3. 3) Perry RJ, et al: Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents. Am J Physiol Endocrinol Metab 311: E461-E470, 2016.
4. 4) Pacini G, et al: Imeglimin increases glucose-dependent insulin secretion and improves β-cell function in patients with type 2 diabetes. Diabetes Obes Metab 17: 541-545, 2015.
5. 5) Funazaki S, et al: A novel mechanism of imeglimin-mediated insulin secretion via the cADPR-TRP channel pathway. J Diabetes Investig 13: 34-41, 2022.
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