Molecular composition of adiponectin in urine is a useful biomarker for detecting early stage of diabetic kidney disease

Author:

Kawano Tomoharu1,Aiba Motohiro1,Ishizu Masashi2,Mori Hiroyasu2,Matsuhisa Munehide2,Hashida Seiichi3,Colpitts Tracey4,Watanabe Toshihiro4

Affiliation:

1. Human Life Science, Tokushima Bunri University, Tokushima, Japan

2. Diabetes Therapeutics and Research Center, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan

3. Department of Diabetes and Molecular Genetics, Ehime University Graduate School of Medicine, Ehime, Japan

4. R&D division, Sysmex R&D Center Americas, Inc., Mundelein, IL, America

Publisher

University of Tokushima Faculty of Medicine

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference12 articles.

1. 1. Levey AS, Eckardt KU, Tsukamoto Y, Levin A, Coresh J, Rossert J, De Zeeuw D, Hostetter TH, Lameire N, Eknoyan G:Definition and classification of chronic kidney disease:a position statement from Kidney Disease:Improving Global Outcomes (KDIGO). Kidney international 67(6):2089-2100, 2005. https://doi.org/10.1111/j.1523-1755.2005.00365.x

2. 2. Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, McCullough PA, Kasiske BL, Kelepouris E, Klag MJ, Parfrey P, Pfeffer M, Raij L, Spinosa DJ, Wilson PW, American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention:Kidney disease as a risk factor for development of cardiovascular disease:a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation 108(17):2154-2169, 2003. https://doi.org/10.1161/01.CIR.0000095676.90936.80

3. 3. Alicic RZ, Rooney MT, Tuttle KR:Diabetic Kidney Disease:Challenges, Progress, and Possibilities. Clinical journal of the American Society of Nephrology:CJASN 12(12):2032-2045, 2017. https://doi.org/10.2215/CJN.11491116

4. 4. Koshimura J, Fujita H, Narita T, Shimotomai T, Hosoba M, Yoshioka N, Kakei M, Fujishima H, Ito S:Urinary adiponectin excretion is increased in patients with overt diabetic nephropathy. Biochemical and biophysical research communications 316(1):165-169, 2004. https://doi.org/10.1016/j.bbrc.2004.02.032

5. 5. Jorsal A, Petersen EH, Tarnow L, Hess G, Zdunek D, Frystyk J, Flyvbjerg A, Lajer M, Rossing P:Urinary adiponectin excretion rises with increasing albuminuria in type 1 diabetes. Journal of diabetes and its complications 27(6):604-608, 2013. https://doi.org/10.1016/j.jdiacomp.2013.06.008

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