Association between Maternal Age and Complications of Pregnancy in Primipara

Abstract

Objectives: The purpose of this study was to analyze the association between maternal age and pregnancy outcome in primipara. Methods: We evaluated retrospectively the clinical characteristics and pregnancy outcomes in primiparous mothers who delivered a fetus after more than 22 weeks of gestation in I hospital from January 2017 to December 2018. Statistical analysis was performed using chi-square tests and multivariable logistic regression. The education, occupation, abortion history, assisted reproductive technology (ART) and multiple pregnancy all showed significantly higher incidence, depending on maternal age (<i>p</i><0.000). Results: The odds ratio in maternal complications was 2.327 times higher in mothers 40 years and above than mothers 29 years and below, and 1.912 times higher in mothers 35-39 years than mothers 29 years and below. The odds ratio in gestational diabetes was 3.337 times higher in mothers 40 years and above than mothers 29 years and below, and 2.698 times higher in mothers 35-39 years than mothers 29 years and below. Conclusions: Consequently, this study showed a significant association between maternal age and pregnancy outcome in primipara. However, as the maternal age increases, the improvement of socioeconomic status and health level are expected to have a greater impact on outcome of pregnancy despite the physical defects of biological aging.