Efficacy of Aloe vera Gel on the Excision Wound Healing in Sprague dawley Rats-Reference-Cited by-同舟云学术

Efficacy of Aloe vera Gel on the Excision Wound Healing in Sprague dawley Rats

Published:2021-08-08 Issue:1 Volume:4 Page:46-49
ISSN:2580-7730
Container-title:Medicra (Journal of Medical Laboratory Science/Technology)
language:
Short-container-title:medicra

Author:

Palgunadi Bagus Uda,Rahayu Asih,Prakoso Yos Adi

Abstract

Wound is a pathological processes in all living things. Wound includes the overlapping mechanisms. The failure in wound healing causes infection. This study aimed to analyze the efficacy of Aloe vera gel in excisionwound on the rat’s back. This study used 18 male, Sprague Dawley rats, and they were induced excision wound on the back. The rats were separated into 3 groups, K1 = control, K2 = treated with betadin gel, K3 = treated with Aloe vera gel. The therapy was given twice a day for 7 days. The wound measurement was observed in day 3 and 7. The data were analyzed using SPSS. The result showed that Aloe vera gel potentially promote wound healing through the decrease microscopical condition of wound, re-epithelialization, and deposition of collagen better than in group K1 and K2 (p≤0.05). In conclusion, Aloe vera gel promote excision wound healing in Sprague Dawley rats.

Publisher

Universitas Muhammadiyah Sidoarjo

Subject

General Medicine

Reference16 articles.

1. Bałan, B. J., Niemcewicz, M., Kocik, J., Jung, L., Skopińska-Różewska, E., & Skopiński, P. (2014). Oral administration of Aloe vera gel, anti-microbial and anti-inflammatory herbal remedy, stimulates cell-mediated immunity and antibody production in a mouse model. Central-European journal of immunology, 39(2), 125–130. https://doi.org/10.5114/ceji.2014.43711.

2. Ceyssens, F., Deprez, M., Turner, N., Kil, D., van Kuyck, K., Welkenhuysen, M., Nuttin, B., Badylak, S., & Puers, R. (2017). Extracellular matrix proteins as temporary coating for thin-film neural implants. Journal of neural engineering, 14(1), 014001. https://doi.org/10.1088/1741-2552/14/1/014001.

3. Chang, A. C., Dearman, B., & Greenwood, J. E. (2011). A comparison of wound area measurement techniques: visitrak versus photography. Eplasty, 11, e18.

4. DePhillipo, N. N., Aman, Z. S., Kennedy, M. I., Begley, J. P., Moatshe, G., & LaPrade, R. F. (2018). Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review. Orthopaedic journal of sports medicine, 6(10), 2325967118804544. https://doi.org/10.1177/2325967118804544.

5. Feldman, A. T., & Wolfe, D. (2014). Tissue processing and hematoxylin and eosin staining. Methods in molecular biology (Clifton, N.J.), 1180, 31–43. https://doi.org/10.1007/978-1-4939-1050-2_3.