Automated Stereotactic Core Needle Biopsy of Microcalcifications with Correlation to Surgical Biopsy

Abstract

Purpose: To compare pathologic findings from stereotactic core and excisional biopsies in patients with microcalcifications in the breast. Material and Methods: Stereotactic core needle biopsies of 101 lesions with mammographic evidence of microcalcifications were performed with long-throw (2.2 cm) automated core biopsy devices fitted with 2.1-mm needles. The core specimens were placed on microscope slides and radiographed. The pathologic features of core and excisional specimens were compared. Results: In 100 of the 101 breast lesions, a correct choice for an additional diagnostic procedure or definitive treatment could have been made upon histo-pathologic findings of the core needle biopsy. Conclusion: Stereotactic core needle biopsy is a reliable alternative to surgical biopsy of breast lesions with microcalcifications provided that specimen radiography has been performed to ensure that appropriate tissue has been obtained. Excisional biopsy may be avoided if microcalcifications are visible in radiographs of core biopsy specimen with benign histology.