Design and Characterisation of Long-R3-Insulin-Like Growth Factor-I Muteins Which Show Resistance to Pepsin Digestion
Author:
Publisher
Informa UK Limited
Subject
Cell Biology,Clinical Biochemistry,Endocrinology
Link
http://www.tandfonline.com/doi/pdf/10.3109/08977199609003227
Reference28 articles.
1. Structural analogs of human insulin-like growth factor I with reduced affinity for serum binding proteins and the type 2 insulin-like growth factor receptor.
2. The roles of tyrosines 24, 31, and 60 in the high affinity binding of insulin-like growth factor-I to the type 1 insulin-like growth factor receptor.
3. Suggestions for “safe” residue substitutions in site-directed mutagenesis
4. Structural Analogs of Human Insulin-like Growth Factor (IGF) I with Altered Affinity for Type 2 IGF Receptors
5. Mutants of human insulin-like growth factor I with reduced affinity for the type 1 insulin-like growth factor receptor
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