Fungal transformations of antihistamines: Metabolism of methapyrilene, thenyldiamine and tripelennamine to N-oxide and N-demethylated derivatives-Reference-Cited by-同舟云学术

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Fungal transformations of antihistamines: Metabolism of methapyrilene, thenyldiamine and tripelennamine to N-oxide and N-demethylated derivatives

Published:1988-01 Issue:3 Volume:18 Page:301-312
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Cerniglia Carl E.,Hansen Eugene B.,Lambert Kenneth J.,Korfmacher Walter A.,Miller Dwight W.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.3109/00498258809041666

Reference21 articles.

1. A Fatality Involving Methapyrilene

2. DNA damage induced by the antihistaminic drug methapyrilene hydrochloride

3. Mutagenicity of amine drugs and their products of nitrosation

4. A study of the potential genotoxicity of methapyrilene and related antihistamines using the hepatocytes/DNA repair assay

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1. Cunninghamella Biotransformation - Similarities to Human Drug Metabolism and Its Relevance for the Drug Discovery Process;Current Drug Metabolism;2016-01-14

2. Production of a new pyridine N-oxide by bioconversion with Cunninghamella echinulata var. elegans;Journal of Bioscience and Bioengineering;2012-11

3. Cunninghamella – A microbial model for drug metabolism studies – A review;Biotechnology Advances;2009-01

4. Identification of the Thiophene Ring of Methapyrilene as a Novel Bioactivation-Dependent Hepatic Toxicophore;Journal of Pharmacology and Experimental Therapeutics;2008-05-01

5. RETRACTED: Biotransformation of drugs by microbial cultures for predicting mammalian drug metabolism;Biotechnology Advances;2003-03

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