Rate-limiting steps in cytochrome P-450-catalysed reactions: Studies on isotope effects in theO-de-ethylation of 7-ethoxycoumarin-Reference-Cited by-同舟云学术

Rate-limiting steps in cytochrome P-450-catalysed reactions: Studies on isotope effects in theO-de-ethylation of 7-ethoxycoumarin

Published:1984-01 Issue:1-2 Volume:14 Page:19-26
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Lu A. Y. H.,Harada N.,Miwa G. T.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.3109/00498258409151396

Reference30 articles.

1. Bjorkhem I. Hepatic Cytochrome P-450 Monooxygenase, International Encyclopedia of Pharmacology and Therapeutics, J. B. Schenkman, D. Kupfer. Pergamon Press, New York 1982; 645–666, Section 108

2. What limits the rate of an enzyme-catalyzed reaction

3. Use of Isotope Effects to Elucidate Enzyme Mechanism

4. Mechanistic deductions from isotope effects in multireactant enzyme mechanisms

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