2 Final Report on the Safety Assessment of Arachidyl Propionate

Abstract

Arachidyl Propionate is an amber-colored semisolid wax, which is used in cosmetics at concentrations up to 10%. Arachidyl Propionate is practically nontoxic when ingested. No systemic toxicity was associated with subchronic oral exposure to Arachidyl Propionate. In test animals, Arachidyl Propionate was neither a primary dermal irritant, nor a skin sensitizer, and it did not have comedogenic potential. It was nonirritating to rabbit eyes. In clinical studies, Arachidyl Propionate was neither an irritant nor a sensitizer. In additional clinical studies, Arachidyl Propionate was neither phototoxic nor a photo-allergen. On the basis of the data included in this report, it is concluded that Arachidyl Propionate is safe as a cosmetic ingredient in the present practices of use and concentration.