Final Report on the Safety Assessment of Sesame Oil

Abstract

Sesame Oil is primarily composed of oleic, linoleic, palmitic, and stearic acids and is used in a variety of cosmetics that come into contact with skin, eyes, hair, and mucous membranes. The oral LD50 of a lipstick containing Sesame Oil (10–11 %) was greater than 5 g/kg. This ingredient is neither a primary skin nor ocular irritant. A formulation containing Sesame Oil was neither a sensitizer nor a photosensitizer. Although not teratogenic, Sesame Oil increased resorptions and deciduomas in mice. Extracts of sesame seeds were not mutagenic with metabolic activation. On the basis of the information presented in the report, it is concluded that Sesame Oil is safe for use as a cosmetic ingredient.