Determination of Toxic Pathways of Metabolism by Deuterium Substitution-Reference-Cited by-同舟云学术

Determination of Toxic Pathways of Metabolism by Deuterium Substitution

Published:1984-01 Issue:7 Volume:15 Page:1335-1351
ISSN:0360-2532
Container-title:Drug Metabolism Reviews
language:en
Short-container-title:Drug Metabolism Reviews

Author:

Pohl Lance R.,Gillette James R.

Publisher

Informa UK Limited

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

Link

http://www.tandfonline.com/doi/pdf/10.3109/03602538409029963

Reference58 articles.

1. The Problem of Chemically Reactive Metabolites

2. Chloroform toxicity in mice: Correlation of renal and hepatic necrosis with covalent binding of metabolites to tissue macromolecules

3. Evidence for the Clara cell as a site of cytochrome P450-dependent mixed-function oxidase activity in lung

4. A prospective on covalent binding and toxicity

5. Buddenbaum W. E., Shinen V. J., Jr. Isotope Effects on Enzyme-Catalyzed Reactions, W. W. Cleland, M. H. O'Leary, D. B. Northrop. University Park Press, Baltimore 1977; 1–36

Cited by 18 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. (R)-Ketamine: A New Rapid-Acting Antidepressant;Contemporary Clinical Neuroscience;2021

2. Deuterium Isotope Effects on Drug Pharmacokinetics. I. System-Dependent Effects of Specific Deuteration with Aldehyde Oxidase Cleared Drugs;Drug Metabolism and Disposition;2011-12-21

3. Solid phase synthesis of selectively deuterated arenes;Chemical Communications;2011

4. Filling and mining the reactive metabolite target protein database;Chemico-Biological Interactions;2009-04

5. Application of Stable Isotope-Labeled Compounds in Metabolism and in Metabolism-Mediated Toxicity Studies;Chemical Research in Toxicology;2008-08-15