Modeling of Sequestration and Down Regulation in Cells Containing Beta2-Adrenergic Receptors

Author:

Barak Larry S.1,Caron Marc G.1

Affiliation:

1. Howard Hughes Medical Institute Laboratories, Dept. of Cell Biology and Medicine, Duke University Medical Center, Durham, NC, 27710

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference19 articles.

1. Schwinn D. A., Caron M. G., Lefkowitz R. J. The beta-adrenergic receptor as a model for molecular structure-function relationships in G-protein-coupled receptors. The Heart and Cardiovascular System-second edition. Raven Press Ltd. 1990; 1657–1683

2. Role of phosphorylation in desensitization of the β-adrenoceptor

3. Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors.

4. Beta-adrenergic receptor sequestration. A potential mechanism of receptor resensitization.

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